Can you believe we first met the ladies of Wisteria Lane 12 years ago? We can't!
' anniversary, click through the gallery below to see the Desperate Housewives cast — including , Eva Longoria , and more! — Felicity Huffman then and now!
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Eva Longoria (Gabrielle Solis)
Desperate Housewives, Eva appeared on shows Mother Up!, Brooklyn Nine-Nine, and Telenovela.
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Nicollette Sheridan (Edie Britt)
Nicollette's career calmed down after she left the drama series. She's appeared in a few TV movies as well as
Jewtopia and Let's Kill Ward's Wife. She's currently on the show Dynasty.
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Vanessa Williams (Renee Perry)
Desperate Housewives, Vanessa added 666 Park Avenue, The Good Wife, Milo Murphy's Law, The Librarians, and Daytime Divas to her acting portfolio.
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Felicity Huffman (Lynette Scavo)
Felicity now stars in the popular TV series
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Teri Hatcher (Susan Mayer)
Teri has since appeared in series
Jane by Design, Jake and the Never Land Pirates, The Odd Couple, and Supergirl.
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Marcia Cross (Bree Van de Kamp)
Desperate Housewives, Marcia appeared in Law & Order: Special Victims Unit and Quantico.
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Brenda Strong (Mary Alice Young)
Brenda has landed roles in
Dallas, Blood Relatives, Fear the Walking Dead, and Supergirl following Desperate Housewives.
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James Denton (Mike Delfino)
James has been on
Devious Maids and Good Witch since Desperate Housewives.
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Ricardo Antonio Chavira (Carlos Solis)
Ricardo has appeared in
Welcome to the Family, Santa Clarita Diet, Jane the Virgin, and Scandal.
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Mark Moses (Paul Young)
Mark has had a very successful career following
Desperate Housewives. He's added The Killing, Criminal Minds, Manhattan, Homeland, Mad Men, The Last Ship, Incorporated, Law & Order True Crime, Salvation, Man Seeking Woman, and more to his acting resume.
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Jesse Metcalfe (John Rowland)
Desperate Housewives, Jesse appeared in Chase, Dallas, and Chesapeake Shores.
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Steven Culp (Rex Van de Kamp)
Steven has since appeared in
Grey's Anatomy, Revolution, Code Black, and Bosch.
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Doug Savant (Tom Scavo)
Doug has made cameos in
Drop Dead Diva, Criminal Minds, Hawaii Five-0, The X-Files, and Notorious.
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Richard Burgi (Karl Mayer)
Today, Richard is most known for his portrayal of Paul Hornsby in
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Alfre Woodard (Betty Applewhite)
Alfre has since appeared in
My Own Worst Enemy, Three Rivers, Memphis Beat, True Blood, State of Affairs, Luke Cage, and A Series of Unfortunate Events.
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Kyle MacLachlan (Orson Hodge)
Kyle has appeared in
How I Met Your Mother, Believe, Agents of S.H.I.E.L.D., Portlandia, and Twin Peaks.
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Dana Delany (Katherine Mayfair)
Dana was seen in
Body of Proof, The Comedians, and Hand of God since Desperate Housewives.
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Neal McDonough (Dave Dash/Williams)
Neil has continued his acting career with roles in
Mob City, Public Morals, Suits, Arrows, and Legends of Tomorrow.
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Drea De Matteo (Angie Bolen)
Drea became well known for her roles in
Sons of Anarchy and Shades of Blue following Desperate Housewives.
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Kevin Rahm (Lee McDermott)
Kevin has appeared in shows
I Hate My Teenage Daughter, Surviving Jack, Mad Men, Bates Motel, Madam Secretary, and now Lethal Weapon.
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Tuc Watkins (Bob Hunter)
Tuc is known for his role on the soap opera
One Life to Live. He also appeared in Where the Bears Are.
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Jonathan Cake (Chuck Vance)
Desperate Housewives, Jonathan was in Doll & Em, Camping, and The Affair.
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Charles Mesure (Ben Faulkner)
Charles has since landed roles in
Girlfriends' Guide to Divorce, Dead of Summer, The Magicians, and Once Upon a Time.
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Kathryn Joosten (Karen McCluskey)
Kathryn sadly passed away at age 72 in June 2012 after battling lung cancer.
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