The Oprah Winfrey Show might have ended six years ago, but the inspirational (and sometimes controversial) guest stars that have appeared on her show are hard to forget. From James Frey to Keisha Thomas, here's a look back at her most memorable guests stars — and where they are now.
Click through the gallery to see whatOprah's most memorable guest stars are up to now.
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In 2006, Oprah chose James Frey's memoir A Little Million Pieces as part of Oprah's Book Club. But shortly after the book's success, reports exposed the book as being partly fiction. Oprah invited James to the show to talk about the controversy and confront him about his many lies.
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James Frey: NOW
Since his controversial appearance on the show, Oprah has since apologized to the author for the harsh way she interviewed him, admitting that she lacked compassion. James has released two other books since Million and runs a young adult publishing company.
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After being savagely attacked by her friend's chimpanzee in 2009, Charla revealed her disfigured face for the first time on Oprah's show.
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Charla Nash: NOW
Since then, Charla has received a face transplant and is now working to pass a bill that will ban primates as pets.
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Keisha made headlines back in 1998 when she shielded a man wearing a confederate flag T-shirt from being beaten by an angry mob. She was praised by Oprah who told her she "did the right thing."
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Keisha Thomas: NOW
Keisha, who now resides in Houston, is still an activist and hopes to return to Michigan to start an organization that helps local businesses, according to Mlive. The man she protected, Albert McKeel Jr., has since died.
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Monica appeared on Oprah back in 2008 to talk about a rare flesh-eating disease that required doctors to amputate both her arms and legs to survive. She came back on the show in 2010 where Oprah surprised her and her family with a brand new house.
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Monica Jorge: NOW
Oprah checked back in with Monica in 2014 for her Where Are They Now? special. Monica said she was doing fine in her new home and that she was still incredibly grateful for Oprah's gift.
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Dennis from Forsyth County, Ga.
Back in 1987, Oprah held a town hall meeting at Forsyth County, Ga., a town that hadn't had a black resident in more than 75 years. Oprah interviewed lots of people from the town, but the most memorable was Dennis, a bearded man who said some infamously racist words.
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Dennis from Forsyth County, Ga.: NOW
Back in 2011, Oprah invited Dennis back to her show. He confessed that his 1987 remarks had left a blight on his reputation. "I would see [people] in the stores and they would go to the next aisle to keep from having to speak to me," he told her. Although he apologized to Oprah for his remarks, he still stood by the majority of what he said.
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Jacqui appeared on Oprah in 2003 to share her harrowing story. After surviving a car crash, caused by a drunk driver, she was left horribly disfigured. She lost her hair, her nose, and was burned all over her body.
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Jacqui Saburido: NOW
Now 37, Jacqui is a spokesperson against drinking and driving. She's also approaching surgeons in hopes she can receive a face transplant.
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Erin and Peyton Kramp
In 1998, Erin became an inspiration thanks to her heartbreaking story. After being diagnosed with breast cancer, Erin recorded hundreds of tapes and videos full of life advice for her daughter, Peyton. Her story moved Oprah to tears.
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Peyton Kramp: NOW
Shortly after the airing of the episode, Erin lost her battle to cancer. Oprah checked back in with the Kramp family twice since Erin's death, the most recent being in 2011.
Peyton made her first appearance at age 13, where she told Oprah she watched her mother's tapes all the time. She's now all grown up and is a Strategy Associate at an agency.
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In 1989, Betty made headlines when she was convicted of murdering her ex-husband and his second wife. She appeared on The Oprah Winfrey Show twice in 1992, with one interview being from prison.
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Betty Broderick: NOW
Betty is still serving time at Calif. Institution for Women in Chino, California. She was denied parole in 2011.