Say it ain’t so!

According to a new report, Drew Barrymore, 41, and her husband, Will Kopelman, have split after nearly four years of marriage.

“They’ve been having some difficulties, but they remain close for the sake of their kids,” an insider told Page Six.

drew barrymore will kopelman getty images

Drew and Will in May 2014.

“Drew had a very rebellious and wild childhood, with no family around her, and while she is a very different person now, and a great mother, some of that can stay with you,” the source added.

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The pair tied the knot in 2012 and are parents to two daughters, Olive, 3, and Frankie, 1.

Neither party has confirmed the split at this time.