Happy birthday, Ellen Pompeo!
To celebrate Dr. Meredith Grey (aka our favorite general surgeon!) turning 46-years-old today, click through the gallery below to see the cast of Grey's Anatomy then and now!
Ellen — who received a Golden Globe nomination in 2007 for her portrayal of Meredith — continues to appear on the show today. The mom-of-three's notable film credits include Moonlight Mile, Old School, Daredevil, and Catch Me If You Can.