Throwback!‘Desperate Housewives’ Turns 12 — See the Cast Then and Now!

Eva Longoria (Gabrielle Solis)

After Desperate Housewives, Eva appeared on shows Mother Up!, Brooklyn Nine-Nine, and Telenovela.

Nicollette Sheridan (Edie Britt)

Nicollette's career calmed down after she left the drama series. She's appeared in a few TV movies as well as Jewtopia and Let's Kill Ward's Wife. She's currently on the show Dynasty.

Vanessa Williams (Renee Perry)

After Desperate Housewives, Vanessa added 666 Park Avenue, The Good Wife, Milo Murphy's Law, The Librarians, and Daytime Divas to her acting portfolio.

Felicity Huffman (Lynette Scavo)

Felicity now stars in the popular TV series American Crime.

Teri Hatcher (Susan Mayer)

Teri has since appeared in series Jane by Design, Jake and the Never Land Pirates, The Odd Couple, and Supergirl.

Marcia Cross (Bree Van de Kamp)

After Desperate Housewives, Marcia appeared in Law & Order: Special Victims Unit and Quantico.

Brenda Strong (Mary Alice Young)

Brenda has landed roles in Dallas, Blood Relatives, Fear the Walking Dead, and Supergirl following Desperate Housewives.

James Denton (Mike Delfino)

James has been on Devious Maids and Good Witch since Desperate Housewives.

Ricardo Antonio Chavira (Carlos Solis)

Ricardo has appeared in Welcome to the Family, Santa Clarita Diet, Jane the Virgin, and Scandal.

Mark Moses (Paul Young)

Mark has had a very successful career following Desperate Housewives. He's added The Killing, Criminal Minds, Manhattan, Homeland, Mad Men, The Last Ship, Incorporated, Law & Order True Crime, Salvation, Man Seeking Woman, and more to his acting resume.

Jesse Metcalfe (John Rowland)

After Desperate Housewives, Jesse appeared in Chase, Dallas, and Chesapeake Shores.

Steven Culp (Rex Van de Kamp)

Steven has since appeared in Grey's Anatomy, Revolution, Code Black, and Bosch.

Doug Savant (Tom Scavo)

Doug has made cameos in Drop Dead Diva, Criminal Minds, Hawaii Five-0, The X-Files, and Notorious.

Richard Burgi (Karl Mayer)

Today, Richard is most known for his portrayal of Paul Hornsby in General Hospital.

Alfre Woodard (Betty Applewhite)

Alfre has since appeared in My Own Worst Enemy, Three Rivers, Memphis Beat, True Blood, State of Affairs, Luke Cage, and A Series of Unfortunate Events.

Kyle MacLachlan (Orson Hodge)

Kyle has appeared in How I Met Your Mother, Believe, Agents of S.H.I.E.L.D., Portlandia, and Twin Peaks.

Dana Delany (Katherine Mayfair)

Dana was seen in Body of Proof, The Comedians, and Hand of God since Desperate Housewives.

Neal McDonough (Dave Dash/Williams)

Neil has continued his acting career with roles in Mob City, Public Morals, Suits, Arrows, and Legends of Tomorrow.

Drea De Matteo (Angie Bolen)

Drea became well known for her roles in Sons of Anarchy and Shades of Blue following Desperate Housewives.

Kevin Rahm (Lee McDermott)

Kevin has appeared in shows I Hate My Teenage Daughter, Surviving Jack, Mad Men, Bates Motel, Madam Secretary, and now Lethal Weapon.

Tuc Watkins (Bob Hunter)

Tuc is known for his role on the soap opera One Life to Live. He also appeared in Where the Bears Are.

Jonathan Cake (Chuck Vance)

After Desperate Housewives, Jonathan was in Doll & Em, Camping, and The Affair.

Charles Mesure (Ben Faulkner)

Charles has since landed roles in Girlfriends' Guide to Divorce, Dead of Summer, The Magicians, and Once Upon a Time.

Kathryn Joosten (Karen McCluskey)

Kathryn sadly passed away at age 72 in June 2012 after battling lung cancer.

The End!